Disillusioned at the thought of taking down another mark, depressed, low-level hit man Barry Berkman (Bill Hader) seeks a way out. When the Midwesterner reluctantly travels to Los Angeles to execute a hit on an actor who is bedding a mobster's wife, little does Barry know that the City of Angels may be his sanctuary. He follows his target into acting class and ends up instantly drawn to the community of eager hopefuls, especially dedicated student Sally (Sarah Goldberg), who becomes the object of his affection. While Barry wants to start a new life as an actor, his handler, Fuches (Stephen Root), has other ideas, and the hit man's criminal past won't let him walk away so easily...