Once inseparable pals, Archie Moses (Adam Sandler) and Rock Keats (Damon Wayans) find themselves on opposite sides of the law, each feeling betrayed by the other. In fact, the only person who hates them more than they hate each other is ruthless drug kingpin Frank Colton (James Caan), who wants to put them both six feet under! Now, through a strange twist of fate, Moses and Keats are on the run - together. With a little luck, the bungling boys just might get out of this one alive... if they don't kill each other first!