When a break-in occurs at a secretive genetics institute, blind puzzle-maker Franco Arnò (Karl Malden), who overheard an attempt to blackmail one of the institute's scientists shortly before the robbery, teams up with intrepid reporter Carlo Giordani (James Franciscus) to crack the case. But before long the bodies begin to pile up and the two amateur sleuths find their own lives imperilled in their search for the truth. And worse still, Lori (Cinzia De Carolis), Franco's young niece, may also be in killer's sights...
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