Uday Gupta (Guddu) a medical student wants to take up Orthology but due to lack of seats he gets enrolled in Gynaecology for which he is least interested. He believes that Gynaecology is a subject made for females as most patients prefer female Doctors at the time of delivery. Due to lack of seats Uday (Ayushmann Khurrana) has to enroll himself in Gynaecology where he has to face brunt from his senior female Doctors. Uday soon befriends his female colleagues one of them being Dr. Fatima Siddiqui (Rakul Preet Singh) but he is still least interested in Gynaecology and still prefers to enter Orthology where he comes under radar of strict Dr. Nandini Shrivastav (Shefali Shah).
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