An ill-fated attempt to re-create the legendary Super-Soldier Serum leads to the development of Extremis, a military nanotechnology serum that directly taps into the body's repair / center, turning an ordinary human being into a super-powered one-man army. Conflict erupts when the Extremis serum is injected into Mallen, a member of a domestic militant group hellbent on avenging the deaths of his family. When a brief battle between Iron Man and Mallen leaves billionaire Tony Stark in critical condition, it becomes clear that the only way for Stark to defeat the Extremis biotech is to use it himself.
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