Young geneticist Max Fleming (James Roday) may be brilliant enough to have created the world's first cloning machine, but when it comes to woman, he's a moron. So when he accidentally clones the girl of his dreams, he seizes the opportunity to create what he feels will be the perfect woman - one who acts just like a guy. He and his friends Henry (Desmond Askew) train the beautiful but uneducated Repli-Kate (Ali Landry) in the "finer" things in life , such as pizza, sports, beer, and, of course sex. All hell breaks loose, however, when the original Kate returns to work with them in the lab, setting up a series of mistaken identities, close calls and major complications.