It's 2199 and radiation from constant Gamilon bombing threatens to destroy life on Earth. Space Cruiser Argo races against time to find the planet Iscander and bring back Cosmo-DNA, which can reverse the contamination.
The Argo engages in spectacular battles with an enemy fleet commanded by Desslok of Gamilon. On board, officers Derek Wildstar and Mark Venture wage their own private war. Chief Mechanic Sandor is revealed to be a Cyborg and Captain Avatar, weakened by radiation poisoning, is kept alive by Dr. Sane, the ship's doctor. A quirky robot called IQ-9 takes over when the human crew need help. All this while Queen Starsha waits on Iscandar with a man from Earth the Star Blazers have given up for dead....
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