Rebellious high school student Tom Majelewski (Tom Bresnahan) is sent to a famed pyschological research institute, where he is unwittingly subjected to mind-control experiments conducted by the institute's mysterious founder, Dr. Blake (David Gale). Plagued by hallucinations, Tom soon learns the institute's terrible secret - an enormous human brain, capable of inducing people to commit random acts of horrible violence. When the brain's hunger becomes insatiable, it remains for Tom alone among the hypnotized citizens to fight off the gruesome threat.
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