A cross-country road trip takes a dangerous detour when driver-for-hire Sean (Kerr Smith) picks up Nick, a hitchhiker (Brendan Fehr) who is on the trail of a band of vampires. At a roadside diner, they encounter a crazed and helpless woman, a recent victim of a vampire feeding. Sean becomes infected with a virus that will eventually turn him into a blood-sucking, flesh-eating vampire. Now, the three must race against time to track down and kill source of the virus: a centuries-old vampire with superhuman strength and an appetite for blood.
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