Helen Hunt joins John Hawkes and William H. Macy in this triumphant true story about love, sex, desire... and making every breath count. Paralysed and confined to an iron lung since childhood, poet-journalist Mark O'Brien (Hawkes) has overcome adversity time and time again. But now, at age 38, he faces his toughest challenge yet: losing his virginity. With the help of a beautiful therapist (Hunt), a sympathetic priest (Macy), and his own unbridled sense of optimism and humour, Mark embarks on an extraordinary personal journey to discover the wondrous pleasures that make life worth living.