In 1943, the year in which the first A-bomb was built, Swiss chemist Albert Hofmann discovered a substance that was to become the A-bomb of the mind. He realized that he was dealing with a powerful molecule that would have an impact not only on the scientific world but on sex, culture and politics. Using previously unreleased archival material and interviews with principal witnesses to the historical events (including Albert Hofmann), The Substance is an investigation into our troubled relationship with LSD, told from its beginnings until today. This is an enlightening trip looking back at Hofmann's legacy, the 20th Century and a look forward to new developments related to LSD.
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